poly(N -isopropylacrylamide)

polymer

Poly(N-isopropylacrylamide), or PNIPAm, is a synthetic polymer known for its temperature-responsive behavior—it exhibits a sharp change in water solubility around 32°C, transitioning from hydrophilic to hydrophobic as temperature rises. This thermosensitive property makes it valuable in biomedical and pharmaceutical applications where controlled release or reversible switching is needed, particularly in drug delivery systems, tissue engineering scaffolds, and smart hydrogels. Unlike conventional polymers, PNIPAm's unique responsiveness to physiological temperature changes has driven adoption in research and clinical development for applications requiring triggered response to body conditions, though it is less common in load-bearing structural applications.

drug delivery systemstissue engineering scaffoldssmart hydrogelsbiomedical coatingstemperature-responsive devicesbiosensors

Compliance & Regulations

?UL 94?Conflict Free?RoHS?REACH?TSCA?Prop 65
Units:
siimperial
PropertyValueUnitConditionsSource
Compressive Strength(σc)
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Elongation at Break(εf)
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Ultimate Tensile Strength(σUTS)
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Young's Modulus(E)
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Verified Unverified Low confidence (<80%) Link to source
PropertyValueUnitConditionsSource
Glass Transition Temperature(Tg)
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Maximum Service Temperature(Tmax)
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Verified Unverified Low confidence (<80%) Link to source
PropertyValueUnitConditionsSource
Refractive Index(n)
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Verified Unverified Low confidence (<80%) Link to source

Regulatory Screening

Environmental

Safety & Biocompatibility

RoHS, REACH, and Prop 65 statuses are validated against official substance lists (ECHA SVHC Candidate List, OEHHA Prop 65, RoHS Annex II). Other regulations are estimated from composition and material classification. All screening is a starting point for due diligence — always verify with your supplier before making compliance decisions.