Bioglass 45S5

Verifiedceramic
· 45S5· Bioglass· NovaBone

Bioglass 45S5 is a silicate-based bioactive ceramic composed of silica, sodium oxide, calcium oxide, and phosphorus oxide that bonds directly to living bone and soft tissue through formation of a hydroxyapatite layer when in contact with biological fluids. It is widely used in orthopedic and dental applications—including bone void fillers, dental implants, periodontal regeneration, and maxillofacial reconstruction—because it promotes osteogenic (bone-forming) response and integrates with native tissue rather than remaining inert like traditional ceramics. Engineers select Bioglass 45S5 when biological integration and resorption are design goals, distinguishing it from inert alumina or zirconia ceramics that encapsulate rather than bond with bone.

orthopedic bone grafts and void fillersdental implants and periodontal regenerationmaxillofacial and craniofacial reconstructionbioactive coatings for metal implantstissue engineering scaffoldsotologic (ear) and spinal fusion applications

Compliance & Regulations

?Conflict Free?RoHS?REACH?TSCA?Prop 65
Units:
siimperial
PropertyValueUnitConditionsSource
Flexural Strength (MOR)(σf)
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ksi——
Fracture Toughness(KIC)
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ksi·√in——
Hardness (Vickers)(HV)
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HV——
Young's Modulus(E)
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ksi——
Verified Unverified Low confidence (<80%) Link to source
PropertyValueUnitConditionsSource
Glass Transition Temperature(Tg)
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°F——
Verified Unverified Low confidence (<80%) Link to source
PropertyValueUnitConditionsSource
Density(ρ)
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lb/in³——
Verified Unverified Low confidence (<80%) Link to source

Regulatory Screening

Environmental

Quality & Standards

Industry-Specific

RoHS, REACH, and Prop 65 statuses are validated against official substance lists (ECHA SVHC Candidate List, OEHHA Prop 65, RoHS Annex II). Other regulations are estimated from composition and material classification. All screening is a starting point for due diligence — always verify with your supplier before making compliance decisions.